If food noise, alcohol interest, libido, or everyday pleasure changes while on a GLP-1, the safest first step is a careful timeline, not a causal leap.
| Signal | Tracker field |
|---|---|
| Low pleasure | 0-10 enjoyment rating for food, hobbies, sex, social time, and movement. |
| Mood | Flat, sad, anxious, irritable, emotionally muted, or normal. |
| Reward changes | Food noise, alcohol interest, shopping/gambling urges, scrolling, or other compulsive loops. |
| Body context | Weight trend, calorie deficit, fatigue, training load, sleep, illness. |
| Medication context | Start date, dose changes, missed doses, restarts, side effects, other medications. |
GLP-1 receptors are involved in appetite and reward biology, and GLP-1 medicines are being studied for alcohol and addictive disorders. That does not mean every change in pleasure, libido, or motivation is caused by the drug. Weight loss, under-eating, sleep disruption, depression, stress, and other medications can all contribute.
The most defensible tracking angle is pattern-finding: what changed, when it changed, and what else was happening.