Research Resources

Source-checked guides to GLP-1 labels, trials, and peptide research.

Educational only — not medical advice.

Practical Guides

GLP-1 pharmacokinetics

Semaglutide & tirzepatide half-life

Read the current labels’ peak-time, half-life, and steady-state facts—and what a modeled level curve cannot measure or predict.

GLP-1 label guide

GLP-1 medications and birth control

What the current Mounjaro, Zepbound, Ozempic, and Wegovy labels say about oral contraceptives and pregnancy planning.

GLP-1 label guide

Wegovy & Zepbound thyroid monitoring

Separate routine monitoring from label language about an already-observed calcitonin result or thyroid nodule.

Working with your prescriber

Build a medication & peptide protocol history

Organize a current product snapshot and dated change log for a clearer, source-checked prescriber handoff.

GLP-1 evidence guide

Semaglutide and diabetic retinopathy

Separate the Ozempic label signal from the post-hoc SUSTAIN 6 explanation—and keep a neutral care-team record.

GLP-1 biomarker guide

Amylase, lipase, and pancreatitis

See what current labels report, why one elevated result is not a diagnosis, and what context to preserve for a clinician.

GLP-1 label guide

GLP-1 medicines and gallbladder risk

Compare the exact Wegovy and Zepbound label incidences, understand the weight-loss evidence boundary, and build a neutral event timeline.

Multi-compound tracking

Keep a multi-compound protocol timeline legible

Use a current roster, dated event timeline, and unresolved-question queue without turning a tracker into an interaction screen.

Study Teardowns

Study teardown

Does Wegovy (semaglutide) protect your heart without diabetes? If you already have heart disease, yes

6.5% vs 8.0% had a heart attack, stroke or cardiovascular death in Novo Nordisk’s 17,604-person SELECT trial. Absolute risk, who was studied, who paid, and side-effect dropouts, with charts from the published numbers.

Study teardown

How much weight will you lose on Zepbound or Mounjaro (tirzepatide)? About 15–21%

Three doses vs placebo over 72 weeks in Eli Lilly’s main weight-loss trial (SURMOUNT-1), side effects in absolute terms, who ran it, and regain after stopping, with charts rebuilt from the published numbers.

Study teardown

How much weight will you lose on Wegovy (semaglutide)? About 15%, and most came back after stopping

What the placebo group got, who ran Novo Nordisk’s main weight-loss trial (STEP 1), dropouts, absolute effects, and regain after stopping, with charts rebuilt from the published numbers.

All study teardowns →

Research Areas

GLP-1 Outcomes

STEP 1 and SELECT, summarized from the trial publications.

Peptide Database

Browse All Peptides

Approved medicines and unapproved research peptides, each with its regulatory status and sources.

Semaglutide Deep Dive

FDA approvals, STEP 1, and SELECT, with primary sources.